Flexible, high-yield nanopore sequencing for every lab


Choose PromethION 2 devices for flexible, high-yield sequencing, in a compact, accessible design. Utilising flow cells that generate hundreds of gigabases, enable PromethION-scale benefits in small to medium sized labs — including cores and commercial service providers. Suitable for users with lower sample processing requirements, up to ~200 flow cells per year.

The PromethION 2 devices allow users to explore their applications and projects, before scaling up to a PromethION 24 or PromethION 48 device if required.

The PromethION 2 Solo (P2 Solo) is now available for purchase through our store. The PromethION 2 (P2) is currently available for pre-order. For more information, see the relevant store pages.


High-resolution touchscreen display

allowing complete device control

Two high-yield flow cells

can be operated individually or together for flexible, on-demand sequencing


16 TB SSD and 128 GB RAM

Standalone, fully integrated device

with powerful NVIDIA A100 GPU for onboard data analysis

A self-contained benchtop nanopore sequencer containing a powerful GPU and running two high-yield PromethION Flow Cells.

Connect to GridION

or existing computer infrastucture

Two high-yield flow cells

delivering up to 580 Gb of data

Flexible, on-demand sequencing

run flow cells individually or together

A compact sequencer for two PromethION Flow Cells, utilising resource within the GridION or other suitable compute, including laptops, to quickly enable accurate, high-yield nanopore sequencing.

Flow Cell Specifications

>100 million cDNA reads for isoform-level analysis
100-200 Gb native gDNA reads (read N50 -25 kb)
50-100 Gb ultra-long native DNA reads (>50 kb read N50)
Multiplexed sequencing of up to 96 samples with PCR or PCR-free barcoding
>200 Gb on metagenomic samples (read N50 ~ 10 kb)

Plus: direct methylation detection, chromatin confirmation capture with Pore-C, direct RNA sequencing, read lengths from short (20 bases) to ultra long (>4 million bases)

Product documentation

PromethION 2 Solo device specs

PromethION 2 Solo Technical Specification

876 KB | PDF Download

PromethION 2 Solo IT requirements

This details the minimum requirements for running PromethION 2 Solo via GridION, or user-provided computer

767 KB | PDF Download

PromethION 2 Solo Quick Start Guide

This checklist represents the minimal requirements for installing the GridION.

217 KB | PDF Download

Safety and regulatory information

110.7 KB | PDF Download

Choosing the right PromethION

Not sure which PromethION device you need? See below for the number of flow cells you can run on a PromethION 2 device, a PromethION 24 or a PromethION 48 each year. Read more about our PromethION 24 and PromethION 48 devices.