TapeStation Instruments

4200 TapeStation System

The 4200 TapeStation system is an established, high-throughput automated electrophoresis platform for nucleic acid sample quality control. Building on the success of the proven ScreenTape technology, it allows fully automated, easy, and reliable analysis of DNA and RNA samples for up to 96 samples per run. The 4200 TapeStation system provides a complete solution for true end-to-end sample quality control in next-generation sequencing (NGS), biobank, or vaccine development workflows.


  • Simplified workflow and minimal hands-on time with fully automated sample processing and the proven, ready-to-use ScreenTape technology
  • Nucleic acid analysis with minimal manual intervention and excellent reproducibility for size, concentration, and integrity
  • Wide range of RNA and DNA ScreenTape applications, including assays for genomic and cell-free DNA
  • Easy switching between DNA and RNA ScreenTape assays for excellent application flexibility
  • Full sample scalability from 1 to 96 samples with constant cost-per-sample
  • Minimized time to results with as little as 1 to 2 minutes per sample or less than 90 minutes for 96 samples
  • Reduced sample consumption with as little as 1 to 2 µL of DNA and RNA samples, even for high-sensitivity assays
  • No risk of cross contamination with individual ScreenTape lanes
  • Reliable integrity standards for RNA (RNA integrity number equivalent, RINe), genomic DNA (DNA integrity number, DIN), and cell-free DNA (%cfDNA)
  • Optimized cost of ownership and maximized instrument uptime with the option for self-maintenance tasks


Depth 510 mm
Dimensions (WxDxH) 435 mm x 510 mm x 445 mm
Height 445 mm
Line Frequency 50-60 Hz
Line Voltage 100-240 VAC
Number of Samples per Run Any number between 1-96
Power Consumption 50 VA
Weight 25.5 kg
Width 435 mm

How It Works

ScreenTape technology

The ready-to-use ScreenTape technology provides fully automated nucleic acid analysis. 16 individual, prefilled ScreenTape lanes minimize experimental preparation, offer full sample scalability and flexibility as partially used ScreenTapes devices can be reused. ScreenTape assays cover a wide range of DNA and RNA QC applications and offer reliable integrity analysis with proven quality metrics for a variety of different sample types while keeping sample consumption to a minimum.

Streamlined analysis

The Agilent TapeStation software offers simple and intuitive instrument control and data analysis. The software automates assay selection and automatically determines sample size, quantity, and integrity providing Agilent’s proven sample quality metrics. The Agilent TapeStation software 5.1 now supports dual instrument control using only one computer.


The 4200 TapeStation system simplifies NGS library QC

The 4200 TapeStation system is a walk away, automated gel electrophoresis solution to qualify and quantify nucleic acid samples during next generation sequencing (NGS) library production. Obtaining information about the integrity of your samples is an essential, time and cost saving step in the NGS workflow. The 4200 TapeStation system with its broad ScreenTape assay portfolio can support you in the NGS library QC and other workflows.