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ZAG DNA Analyzer Systems

ZAG DNA Analyzer Software

The Agilent ZAG DNA Analyzer system relieves bottlenecks in automated high-throughput DNA fragment analysis workflows. Using parallel capillary electrophoresis, the ZAG DNA Analyzer system can process thousands of DNA fragment samples a day, eliminating bottlenecks associated with agarose gels.

This system is ideal for a range of DNA fragment applications, from basic PCR fragment analysis to microsatellite detection. Minimal sample preparation, automated separation of samples, and the option for continuous operation help keep your workflow moving.

Features

  • High Separation Resolution - Reliably distinguish and size DNA fragments within 3 bp of each other
  • High Throughput - Process 48, 96-well sample trays in 24 hours.
  • Broad Sizing Range - Size fragments between 35 bp and 20,000 bp through a variety of available DNA analysis kits.
  • Fast Separation Times - Samples can be separated in as little as 20 minutes.
  • Intuitive Data Analysis - Analytical software can process separation data automatically after the run and generate a report in multiple formats.
  • Desktop PC supplied with a comprehensive 3-year warranty through HP

Specifications

Ambient Temperature 20-23 °C
Dimensions (WxDxH) 63 cm x 61 cm x 66 cm
Kit Type Qualitative
Line Frequency 47-63 Hz
Line Voltage 100-240 VAC
Number of Samples per Run 96
Operating Environment Relative Humidity 20-80 %
Power Consumption 150 VA
Weight 68 kg

How It Works

Alleviating Bottlenecks in DNA Fragment Analysis

DNA fragment analysis is a crucial procedure in many molecular biology laboratories. In high-throughput molecular biology settings, analysis of DNA fragments often poses a bottleneck as conventional analytic methods, such as agarose gel electrophoresis, do not scale up well. The ZAG DNA Analyzer alleviates these DNA fragment analysis bottlenecks allowing labs to quickly and accurately perform fragment analysis on DNA samples up to 20,000 bp in size.

Analyze 96 Samples in Parallel

An integral component of the ZAG DNA Analyzer is the award winning 96-capillary array. The patented technology is centered on a parallel capillary set up which allows simultaneous injection of up to 96 individual samples from a standard well plate. The capillaries are arranged into a tight formation and illuminated with a single, high powered LED light source. This allows the CCD camera to detect the DNA fragments, bound with intercalating dye and emitting a fluorescent signal, as they move through the capillaries.

Batch Processing and Flagging Simplify High Throughput Analysis

Over 100 sample plates can be processed at the same time using the Batch Processing mode in ProSize. Users are notified about samples that do not meet batch specifications. Specific flagging criteria can be applied to each run for report generation. Individual flag criteria can be established for each capillary separately or criteria can be set to an entire plate. A plate map with specific flagging criteria designated per capillary can be saved and loaded for reapplication to future runs. Data can be output in either CSV or PDF.

applications

Automated fragment analysis with the ZAG DNA Analyzer system

The Agilent ZAG DNA Analyzer system is a highly efficient, automated DNA fragment analysis system for high-throughput workflows such as genotyping, PCR amplicons, restriction digests, and microsatellite analysis. The robust ZAG DNA Analyzer runs thousands of DNA fragment samples per 24 hours. It provides high resolution of separation and reliable sizing information for a broad range of DNA fragment sizes between 35 and 20000 base pairs. The low sample volume and short run time abilities of the ZAG DNA Analyzer make it excellent for rapid qualification analysis of DNA fragments.